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Thyroid Examination

An 11-step thyroid examination assessing thyroid status, the eyes and the neck, including comments on findings.

Endocrinology · Self-paced

11 sections · 53 actionable steps

Before you begin

Equipment

Glass of water

Sheet of paper for tremor

Stethoscope

Tendon hammer

Watch with a second hand

The aim

Decide the patient’s thyroid status, then describe the gland.

The hands, pulse and face tell you if the patient is hyper-, hypo- or euthyroid. The eyes and neck point to the cause.

How to use this guide

Read it through: Learn the sequence and the reason behind each step before you practise.

Practise in pairs: One examines, one reads the steps aloud and ticks each circle as it is completed.

Present aloud: Finish every attempt with a concise summary, as you would for an examiner.

The sequence

Talk

Introduce, consent, position

Status

General, hands, pulse, face

Eyes

Inspect, lid lag, movements

Neck

Inspect, swallow, palpate

Close

Percuss, bruit, legs

Step 1. Introduction

  • Hand hygiene

    Hand wash/rub

  • Introduce yourself

  • Explain the purpose

  • Obtain consent

  • Ask about pain

    Ask about any pain or tenderness in the neck before you touch it

  • Position and exposure

    Sit the patient upright on a chair with room to stand behind them. Expose the neck down to the clavicles

  • Glass of water

    Have a glass of water ready for the swallow test

Set up first

Use a chair away from the wall so you can stand behind the patient. Pour the water before you begin.

Status first, gland second

Every finding from the hands to the face answers one question: is this patient hyper-, hypo- or euthyroid?

Step 2. General Inspection

  • Body habitus

    Weight loss or weight gain

  • Demeanour

    Anxious, restless and fidgety, or slow and lethargic

  • Dress for the temperature

    Under-dressed and sweaty (heat intolerance) or wrapped up warmly (cold intolerance)

  • Voice

    Hoarse or slow speech

  • Surroundings

    Look for medications, a fan or extra blankets around the patient

Step 3. The Hands

  • Temperature and sweating

    Warm and moist palms, or cool and dry skin

  • Palmar erythema

    Reddening of the thenar and hypothenar eminences

  • Onycholysis

    Separation of the nail from the nail bed (Plummer’s nails)

  • Thyroid acropachy

    Clubbing-like finger swelling with periosteal new bone, seen in Graves’ disease

  • Fine tremor

    Arms outstretched, fingers spread. Lay a sheet of paper over the hands to exaggerate the tremor

Graves’ in the hands

Thyroid acropachy is specific to Graves’ disease. Tremor, sweating and onycholysis occur in any cause of thyrotoxicosis.

Step 4. The Pulse and Arms

  • Radial pulse

    Rate and rhythm over at least 30 seconds: tachycardia or atrial fibrillation, or bradycardia

  • Proximal myopathy

    Arms abducted to 90°, ask the patient to resist as you push down on the upper arms

  • Biceps reflex

    Brisk in hyperthyroidism; slow to relax in hypothyroidism

  • Blood pressure — comment only

    Comment only — do not perform

    Wide pulse pressure in hyperthyroidism; diastolic hypertension in hypothyroidism

Always check the rhythm

Atrial fibrillation is a common complication of thyrotoxicosis, especially in older patients.

Step 5. The Face

  • Skin

    Dry, coarse or pale skin; a malar flush

  • Hair

    Diffuse thinning, or dry and coarse hair

  • Eyebrows

    Loss of the outer third of the eyebrows

  • Periorbital puffiness

    Seen in hypothyroidism

  • Tongue

    Macroglossia in severe hypothyroidism

Step 6. The Eyes

  • Inspect from the front

    Lid retraction: sclera visible above the iris. Conjunctival injection and chemosis

  • Inspect from the side and above

    Stand behind the patient and look down over the forehead for exophthalmos (proptosis)

  • Lid lag

    Ask the patient to follow your finger from above eye level down to the floor. Look for sclera above the iris as the eye moves down

  • Eye movements

    Test in an H pattern, keeping the head still. Ask about double vision or pain on movement

Lid lag or exophthalmos?

Lid retraction and lid lag occur in any thyrotoxicosis. Exophthalmos, chemosis and ophthalmoplegia point to Graves’ disease.

Move slowly

Move your finger slowly during the lid lag test and hold it about 50 cm from the face.

Examiner note

Offer visual acuity, colour vision and fundoscopy if there are features of Graves’ eye disease.

Step 7. Inspection of the Neck

  • Inspect from the front

    Midline or lateral swelling, scars (a collar incision from thyroidectomy), skin changes and distended veins

  • Inspect from the side

    Look at the profile of the neck for a subtle goitre

  • Swallow test

    Sip of water, hold it in the mouth, then swallow. A thyroid swelling rises with swallowing

  • Tongue protrusion

    Ask the patient to stick out their tongue. A thyroglossal cyst rises with tongue protrusion

Why it moves

The thyroid sits inside the pretracheal fascia, so it rises on swallowing. A thyroglossal cyst is tethered to the tongue.

Describe a lump

Site, size, shape, surface, consistency, tenderness, mobility, and whether you can get below it.

Step 8. Palpation of the Neck

  • Warn the patient

    Explain that you will stand behind them and feel the neck

  • Find the isthmus

    Neck slightly flexed. Palpate in the midline from the cricoid cartilage down to the sternal notch

  • Palpate each lobe

    Size, shape, consistency, tenderness, nodules and mobility. Retract the sternocleidomastoid to feel each lobe

  • Palpate while swallowing

    Ask the patient to swallow again and feel the gland rise; try to get below it

  • Palpate with tongue protrusion

    For a midline lump, feel whether it rises as the tongue is protruded

  • Cervical lymph nodes

    Submental, submandibular, pre- and post-auricular, occipital, cervical chains and supraclavicular nodes

  • Trachea

    From the front, check that the trachea is central

Stand behind

Keep the neck slightly flexed to relax the strap muscles. Use the pads of both hands and keep watching the patient’s face for pain.

Step 9. Percussion and Auscultation

  • Percuss the manubrium

    Dullness over the upper sternum suggests retrosternal extension of a goitre

  • Auscultate each lobe

    Listen with the diaphragm for a thyroid bruit; ask the patient to hold their breath

  • Pemberton’s sign

    Ask the patient to raise both arms above the head for one minute. Facial plethora, distended neck veins or stridor suggest thoracic inlet obstruction

Bruit or murmur?

A thyroid bruit suggests the increased blood flow of Graves’ disease. Listen over the aortic area to exclude a radiating murmur.

Step 10. The Lower Limbs

  • Pretibial myxoedema

    Raised, firm, pink-brown plaques over the shins, seen in Graves’ disease

  • Peripheral oedema

    Non-pitting oedema in hypothyroidism

  • Proximal myopathy

    Ask the patient to stand from the chair with their arms crossed

  • Ankle reflexes

    Brisk in hyperthyroidism; slow-relaxing in hypothyroidism. Test with the patient kneeling on a chair if needed

Hung-up reflexes

A slow relaxation phase after the ankle jerk is a classic sign of hypothyroidism.

Step 11. Conclusion

  • Thank the patient

    Thank the patient and help them to cover up

  • Hand hygiene

    Hand wash/rub

  • State the thyroid status

    Clinically hyperthyroid, hypothyroid or euthyroid

  • Describe the neck

    Diffuse goitre, multinodular goitre, solitary nodule or no palpable abnormality

  • Suggest further investigations

    Thyroid function tests, thyroid antibodies, ultrasound of the neck and fine-needle aspiration if a nodule is found

Finish strongly

Give the thyroid status first, then the neck findings and eye signs, then your likely diagnosis and investigations.

Run it from memory

Cover the steps and recite the sequence.

  1. Step 1. Introduction
  2. Step 2. General Inspection
  3. Step 3. The Hands
  4. Step 4. The Pulse and Arms
  5. Step 5. The Face
  6. Step 6. The Eyes
  7. Step 7. Inspection of the Neck
  8. Step 8. Palpation of the Neck
  9. Step 9. Percussion and Auscultation
  10. Step 10. The Lower Limbs
  11. Step 11. Conclusion

What your findings mean

Thyroid status at a glance

Check each finding against both columns.

Thyroid status at a glance
FeatureHyperthyroidismHypothyroidism
GeneralWeight loss, anxious, restless, heat intolerantWeight gain, slow, lethargic, cold intolerant
HandsWarm and sweaty, fine tremor, onycholysis, palmar erythemaCool and dry, carpal tunnel signs
PulseTachycardia, atrial fibrillation, wide pulse pressureBradycardia, diastolic hypertension
Face and hairDiffuse hair thinningDry coarse hair, loss of outer third of eyebrows, periorbital puffiness, hoarse voice
EyesLid retraction and lid lagPeriorbital oedema
Muscles and reflexesProximal myopathy, brisk reflexesProximal myopathy, slow-relaxing reflexes, non-pitting oedema

Types of goitre

Types of goitre
TypePossible causes or description
Diffuse, smoothGraves’ disease, Hashimoto’s thyroiditis, iodine deficiency, puberty and pregnancy
MultinodularToxic or non-toxic multinodular goitre
Solitary noduleCyst, adenoma, carcinoma, or a dominant nodule within a multinodular goitre
TenderSubacute (de Quervain’s) thyroiditis, or bleeding into a cyst

Signs of Graves’ disease

Signs of Graves’ disease
AreaSigns
EyesExophthalmos, chemosis, ophthalmoplegia
SkinPretibial myxoedema
HandsThyroid acropachy
NeckDiffuse smooth goitre with a bruit

Midline neck lump

Midline neck lump
Moves withLikely cause
Swallowing onlyThyroid
Swallowing and tongue protrusionThyroglossal cyst
NeitherLymph node, dermoid or lipoma

Act on these findings

Stridor or a positive Pemberton’s sign — possible airway compression; urgent review.

Reduced vision or colour vision in Graves’ eye disease — possible optic nerve compression; emergency ophthalmology.

Fever, tachycardia, agitation or confusion in thyrotoxicosis — consider thyroid storm.

Hard, fixed nodule, nodes or a hoarse voice — suspect malignancy; urgent ultrasound and FNA.

Presenting your findings

Model presentation

“I examined Ms Patel, a 34-year-old woman, who appeared slim, anxious and restless. Her palms were warm and sweaty, with a fine tremor and onycholysis. Her pulse was 112 and irregularly irregular. She had bilateral exophthalmos with lid retraction and lid lag, and full eye movements without diplopia.

There was a diffuse, smooth, non-tender goitre that rose with swallowing but not with tongue protrusion, with a bruit over both lobes. There was no retrosternal dullness or lymphadenopathy, and Pemberton’s sign was negative. Reflexes were brisk. She is clinically hyperthyroid, and these findings are consistent with Graves’ disease complicated by atrial fibrillation.”

Structure

Structure
StepInclude
01 · WhoName, age, setting
02 · StatusHyper-, hypo- or euthyroid
03 · EyesThyrotoxic or Graves’ signs
04 · NeckType of goitre, nodes, airway
05 · ConcludeDiagnosis and next steps

Common pitfalls

Not stating the thyroid status

Palpating from the front only

Standing behind without warning the patient

Forgetting the tongue protrusion test

Skipping retrosternal percussion and Pemberton’s sign

Calling lid lag exophthalmos

To complete the examination

Thyroid function tests: TSH, free T4 and T3

Thyroid antibodies: TRAb, anti-TPO

Ultrasound of the neck, with FNA for nodules

Radioisotope uptake scan if thyrotoxic

ECG if the pulse is irregular

Ophthalmology review if eye signs are present

Sources

Checklist steps: written in the med study partner examination checklist format.

Further reading: Talley NJ, O'Connor S. Clinical Examination: A Systematic Guide to Physical Diagnosis. Elsevier. Macleod’s Clinical Examination. Elsevier.

Always follow your own medical school's marking criteria and local clinical policies.

Educational use only

Made for learning, not for clinical decision-making.

Educational only. Not medical advice or a substitute for supervised clinical training.

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